Top Y Combinator Startups in Boston 2023

December 2023

Browse 83 of the top startups funded by Y Combinator. Headquartered in Boston, these are some of the hottest and fastest-growing startups.

We also have a Startup Directory where you can search through over 4,000 companies.

  • Ginkgo Bioworks
    Ginkgo Bioworks (S14)Public • 641 employees • Boston
    Ginkgo Bioworks is the organism company. We design custom organisms for customers across multiple markets. We build our foundries to scale the process of organism engineering using software and hardware automation. Organism engineers at Ginkgo learn from nature to develop new organisms that replace technology with biology.
    synthetic-biology
    diagnostics
    automation
  • Vendr.com
    Vendr.com (S19)Active • 338 employees • Boston
    Vendr helps software buyers pay less for software and helps software sellers acquire customers at a lower CAC -- a no brainer for both buyers and sellers. $4 billion+ of software transacted on Vendr, across 2,500+ software sellers.
    saas
    procurement
  • Panorama Education
    Panorama Education (S13)Active • 450 employees • Boston
    Panorama is a fast-growing national technology company focused on improving education. More than 2,000 school systems serving 15 million students across 50 states have adopted our platform to understand students’ academic and social-emotional strengths and to identify those in need of additional support. School systems turn to Panorama's suite of tools to ensure that every child gets the support they need, including school climate and social-emotional learning surveys, tiered intervention planning, and professional development.
    education
    saas
    b2b
  • Gecko Robotics
    Gecko Robotics (W16)Active • 230 employees • Austin, TX
    The mission of Gecko Robotics is to improve the state of the world by helping the most important institutions ensure the availability, reliability and sustainability of critical infrastructure. Gecko's combination of wall-climbing robots, industry-leading sensors, and an AI-powered data platform give customers a unique window into the health of their physical assets allowing real-time decisions that prevent power outages, ensure military missions succeed, and help reduce energy costs.
    robotics
    energy
    big-data
    data-engineering
    ai
  • Sendwave
    Sendwave (W12)Acquired • 350 employees • Boston
    Sendwave's mission is to make sending money as easy and affordable as sending a text. Our app sends transfers securely from North America and Europe to Africa, Asia, and the Americas at great rates.
    fintech
    payments
  • REGENT
    REGENT (W21)Active • 40 employees • North Kingstown, RI
    REGENT is building a new mode of transportation that will redefine regional mobility by mid-decade. Their first product, the seaglider, is an all-electric, hydrofoiling boat-plane that operates within a wingspan of the water's surface. By flying low on a cushion of air, seagliders unlock the ability to fly twice as far as an electric aircraft, while being regulated by maritime authorities enabling market entry for a fraction of the cost. REGENT has de-risked seaglider technology with a ¼-scale, 400 lb, flying demonstration vehicle and a full-scale wing test section. By 2024, REGENT will fly humans on the first full-scale prototype seaglider. By mid-decade, REGENT’s customers - airlines and ferry companies – will begin commercial seaglider service on the 12-seat initial product. In just two years, REGENT has accumulated $8B in provisional orders (including firm deposits) proving the potential of the $25B+ initial market. REGENT, a team of 40, is led by MIT-trained, ex-Boeing engineers Billy Thalheimer and Mike Klinker. REGENT has raised $50M to date from the likes of Thiel Capital, Founders Fund, Mark Cuban, Y Combinator, and includes strategic investment from Japan Airlines, Hawaiian Airlines and Mesa Airlines.
    climate
    electric-vehicles
    aerospace
    maritime
  • Legacy
    Legacy (S19)Active • 35 employees • New York
    **TL;DR:** Legacy (YC S19) is a Series B startup focused on the fast-growing field of fertility and family planning. Founded at Harvard, the company has now raised almost $50M from leading investors like FirstMark Capital, Bain Capital Ventures, Section 32, Tribe Capital, and even celebrities like Justin Bieber, The Weeknd, and others. For context, we've closed 4 venture rounds in 2.5 years, in addition to our celebrity round of funding. **What we're doing** We are building a complete digital health hub for future fathers/parents. We aim to change the outdated view that fertility is a "women's issue" by creating an accessible, affordable product for men & people with sperm. This includes everything from a mail-in kit for sperm testing & sperm freezing, personalized sperm improvement products, tele-health, DNA fragmentation analysis, supplements, and more. **Why are we the leader?** The company was founded at Harvard by a team of healthcare and fertility experts. We obsess about talent density and have out-executed our competitors over the past few years. Beyond our D2C channel, we've also unlocked: 1. Insurance (We cover over 10M individuals through insurance in NY and CA) 2. Military (We serve the Navy SEALs & other SpecOps through exclusive programs) 3. Employers (We work with the top fertility benefit providers like Progyny, Carrot, and Maven) **Tell me about the team** We're a team of under 50, extremely diverse (majority female, majority immigrants, strong LGBQTIA+ representation, age range of 25-65), and very values driven. Our 5 values are customer centricity, reliability, kindness, openness, and winning. Learn more about our values here: https://khaled-legacy.medium.com/legacys-values-and-why-they-matter-db116539d3da Learn more about our workplace here: https://khaled-legacy.medium.com/how-and-why-legacy-is-reinventing-workplace-benefits-9e5fda6cb863 Read about our mission to humanize the path to parenthood: https://khaled-legacy.medium.com/how-and-why-legacy-is-reinventing-workplace-benefits-9e5fda6cb863 Learn more about sperm and why it matters here: docsend.com/view/zkgk7ws
    fertility-tech
    cryogenics
    consumer-health-services
  • Nectar
    Nectar (S23)Active • 2 employees • New York
    Nectar helps large companies collect carbon emissions data for mandatory disclosures. Over 50,000 large companies today are required to collect utility data for upcoming regulations in the US/EU. Today, sustainability teams manually parse the data, a process that takes 100M work hours annually, requires expensive audits, and results in inaccurate ESG scores 10% of the time. Nectar automatically extracts, structures, and inputs this data into existing ESG software. After launching just one month ago in YC, we already signed contracts with two F500 companies.
    b2b
    climate
    enterprise-software
    climatetech
  • Fairway Health
    Fairway Health (W23)Active • 3 employees • New York
    Fairway Health is an AI-assistant for health insurers to quickly process patient treatment authorizations. We use LLMs to analyze long (70+ page), messy medical records and determine if a patient is eligible for a treatment.
    health-tech
    b2b
    healthcare
    health-insurance
    ai
  • Pledge Health
    Pledge Health (W23)Active • 2 employees • New York
    Pledge automates patient billing for independent healthcare clinics. We estimate how much insurance will cover for each visit, so clinics can charge patients at the time of service, rather than waiting weeks for insurance to process.
    fintech
    saas
    health-tech
    b2b
    workflow-automation
  • Guardian Bio
    Guardian Bio (S22)Active • 2 employees • Boston
    Your immune system is your body’s best weapon and defense against cancer. It is only when it is overcome that cancer develops into full blown disease. Dendritic cells sit at the helm of the immune system, directing and dictating immune responses. Data has shown dendritic cells are often dysfunctional in cancer patients, and that this dysfunction is a bottleneck for other therapies. Guardian Bio’s approach is focused on creating a dendritic cell-based product which drives anti-tumor activity through activating the killers of the immune system AND training them against multiple cancer targets. We take stem cells from cancer patients, turn them into specific therapeutic dendritic cells specially trained against that patient’s tumor, and re-introduce them back into the body. Our therapeutic dendritic cells revitalize the killers of the immune system and give them the kickstart they need to fight - and win - against cancer.
    biotech
    healthcare
    therapeutics
    oncology
  • Mendable
    Mendable (S22)Active • 4 employees • Boston
    We’re building a chat-powered search tool that’s embeddable in your docs, product, or community to answer developer questions and reduce their time to hello world. Previously SideGuide.
    artificial-intelligence
    developer-tools
    b2b
    customer-support
  • Illuminant Surgical
    Illuminant Surgical (S22)Active • 4 employees • Cambridge, MA
    Illuminant is helping surgeons perform safer and more efficient surgeries by projecting visual guidance directly on the patient’s skin. Using computer vision and low cost hardware, we can display patient-specific anatomical structures from preoperative medical images (e.g. CT scans), pre-operative annotations from planning, and real-time feedback, like needle depth and tool trajectory, as a surgeon operates. Our vision is to expand surgical navigation to underserved health systems and surgical specialties.
  • Overwatch
    Overwatch (S22)Active • 5 employees • New York
    Overwatch Data offers real-time, actionable intelligence tailored for your fraud, security, and strategic insights teams. Our platform provides a comprehensive and contextualized view of opportunities and risks, drawing on the surface, social, and deep web, thereby enabling faster, data-driven decision-making.
    artificial-intelligence
    saas
    supply-chain
  • NuMind
    NuMind (S22)Active • 6 employees • Cambridge, MA
    NuMind is a tool for data scientists, data analysts, but also software engineers to create custom NLP models. For example, a recruiting company uses NuMind to find which job offers best match a given resume. Etienne (CEO) was head of Machine Learning at Wolfram Research, and Samuel (CTO) co-founded Make.org (8M users). NuMind originated from our own frustration when developing NLP models. Leveraging large language models similar to GPT-3, NuMind allows to complete NLP projects at least 10x faster than before. We launched a private beta August 2 and had 9 paying customers one month later.
    aiops
    artificial-intelligence
    machine-learning
    nlp
  • WhiteLab Genomics
    WhiteLab Genomics (W22)Active • 25 employees • Paris, France
    We have developed an AI platform enabling to accelerate the discovery and the design of genomic therapies such as Cell Therapies, RNA Therapies and DNA Therapies.
    artificial-intelligence
    gene-therapy
    cell-therapy
    genomics
  • Reviving Mind
    Reviving Mind (W22)Active • 3 employees • Boston
    Navigating chronic illness is an isolating and lonely process which ultimately reduces medical adherence and adversely impacts outcomes. There are over 100 deadly chronic conditions as 1 out of 2 Americans is currently living with at least 1 chronic condition. The US healthcare system has over $1 trillion dollars in direct costs. Medical adherence rates for therapeutic programs and medicine are only 50% because patients feel lonely, isolated, and unsupported in their chronic illness journey. Reviving Mind is an in-network telehealth provider that improves clinical outcomes and program adherence for the senior medicare and medicare-advantage population that is plagued with loneliness and chronic illness. This is done through a novel and proprietary clinical program and technology platform that integrates virtual, private, curated, and professionally led groups that scale up to 8-patients with individualized and goal oriented lifestyle medicine coaching that is automated but managed by a licensed provider. Scaling rapidly across the United States.
    consumer-health-services
    digital-health
    healthcare
    telemedicine
  • Yatima Inc.
    Yatima Inc. (W22)Active • 7 employees • Boston
    Yatima is a verifiable computing platform which uses formal proofs and zkSNARKs to make software safer.
    fintech
    hard-tech
    crypto-web3
    security
  • Neural Dynamics Technologies Inc.
    Neural Dynamics Technologies Inc. (W22)Active • 5 employees • Boston
    We create high-resolution, minimally invasive electrodes for sensing and stimulating neural activity within the brain with the goal of transforming the efficacy of deep brain stimulation (DBS), an FDA-approved therapy used to treat Parkinson’s, essential tremor and epilepsy. NDT's electrode leads are thinner than a human hair and unlike currently available DBS devices, our devices do not only stimulate, but also sense brain activity, thereby enabling high-resolution, closed-loop recording and stimulation in the brain.
    neurotechnology
    medical-devices
    biotech
  • Beam
    Beam (W22)Active • 4 employees • New York
    Instantly run code on GPUs, deploy scalable web APIs, mount storage volumes, and schedule cron jobs. Beam is your swiss army knife for running code on the cloud.
    artificial-intelligence
    developer-tools
    machine-learning
  • Brown Foods
    Brown Foods (W22)Active • 4 employees • Boston
    Brown Foods is a Stanford, Rice University and IIT Delhi alumni venture building the next-generation of food products. They are creating UnReal Milk- lab based, clean milk - extremely sustainable 'real milk' but made without any cows. Unlike any other option in the USD 22 billion dairy alternatives market today, it will be exactly similar to cow’s milk in terms of nutritional profile, taste, texture and could also be processed into butter, cheese and ice creams. They envision to disrupt the USD 700 billion conventional dairy market by giving the world its 1st 'cow free' real milk option, reducing the carbon footprint of milk by over 90% while being completely cruelty-free.
    cellular-agriculture
    biotech
    climate
    food-tech
  • Medium Biosciences
    Medium Biosciences (S21)Active • 6 employees • Boston
    Our product is a software platform that makes it really easy for industrial biotechnology companies to interface with machine learning models for enzyme engineering. Enzymes power most chemical reactions in nature but usually need engineering to work at industrial scale. Our models can be used to suggest high performing sequences that would have typically taken months of wet lab work to identify.
    machine-learning
    saas
    climate
  • Mindmesh
    Mindmesh (S21)Active • 7 employees • Boston
    Mindmesh is the virtual desk that puts you in control. Centralize work, notes, todos, and meetings. Jump back in an instant. Focus on what you should be doing, right now.
    saas
    productivity
    remote-work
  • Kiwi Biosciences
    Kiwi Biosciences (S21)Active • 6 employees • Boston
    Kiwi Biosciences can help 18M Americans suffering from Irritable Bowel Syndrome (IBS) enjoy a normal meal without running to the bathroom two hours later. We develop novel, patent-pending enzymes that break down common digestive triggers in food.
    biotech
    food-tech
  • KaiPod Learning
    KaiPod Learning (S21)Active • 4 employees • Boston
    KaiPod Learning works with middle- and high-school students who go to school online. We provide a physical place for these students to work on their classes, to interact with other students, and to get support from teachers. Our founder was the CPO of Pearson Online Schools and knows that despite all the noise around online learning, millions of kids thought it was the best school they ever had! But they *needed* a place to go for in-person support. In our summer pilot, we tripled the rate of academic progress *and* received an NPS of 100. Now, we have 12 pods operating around the country and are supporting 175+ students. After COVID, we will see at least 5 million students opt-in to online learning and we will license our platform and approach to anyone who supports these students.
    education
    elearning
    consumer
  • SenpAI.GG
    SenpAI.GG (S21)Active • 12 employees • Boston
    SenpAI.gg is a gaming coach for the 1.4 billion PC gamers globally. SenpAI.gg’s desktop application makes personalized recommendations in the game and provides post-game feedback to help gamers improve faster. It is the most comprehensive assistant that supports gamers before and during the game via Voice Assistant, or an overlay that uses computer vision. The company is Boston-based and founded by Olcay Yilmazcoban (MIT researcher & gamer) and Berk Ozer (engineer & gamer). We raised $3M seed funding (ACT Venture Partners) and we are in the Summer 2021 Batch of Y Combinator. https://senpai.gg/
    artificial-intelligence
    assistive-tech
    gaming
  • Pirouette Medical
    Pirouette Medical (S21)Active • 9 employees • Boston
    At Pirouette, we have developed a low-profile, disk-shaped, rugged injection device with a patient-centric focus on affordability, portability, and usability. The patented device, based on extensive patient input, is designed to make administering an injection as easy as pushing a button. This allows individuals with limited or no training to easily and intuitively perform an injection on themselves or others.
    health-tech
    medical-devices
  • Kodex
    Kodex (S21)Active • 3 employees • Boston
    Kodex makes it easy for companies to process, and respond to, subpoenas from governments around the world. Agencies, like the FBI, subpoena user data from customers like Coinbase, and thousands of other companies - without Kodex, companies largely rely on email, fax, and spreadsheets to manage them. Kodex is a SaaS tool that helps private sector companies manage relationships, workflows, and secure file transfer with government agencies who are seeking confidential information on a company's users. We streamline compliance operations, protect the privacy of their users, reduce error, and validate the legitimacy of government agents who are requesting information. To date, we have launched with Coinbase, Kik Messenger, Whisper App, & Amino Apps. These companies alone receive over 20,000 data requests per year.
    compliance
    legaltech
    regtech
  • AOA Dx
    AOA Dx (S21)Active • 6 employees • New York
    AOA Dx Inc has partnered with a leading researcher at McGill University to develop the first early stage ovarian cancer liquid biopsy diagnostic test. The co-founders have worked together at two previous startups in the women’s health space, both resulting in successful exits upon commercialization. Ovarian cancer is the deadliest gynecological disease because there is no accurate testing method and therefore its symptoms are continuously mistaken for benign conditions, making it incredibly difficult to diagnose the disease in the early stages. The team has previously raised a $7M Seed round and completed a 500+ retrospective patient study showing excellent sensitivity and specificity. Ovarian cancer is just the beginning. AOA has a platform of novel ganglioside tumor markers to disrupt early cancer detection.
    diagnostics
    women's-health
    femtech
  • Promakhos Therapeutics
    Promakhos Therapeutics (S21)Active • 2 employees • Boston
    We are building a platform of bacterial molecules to awaken our body’s innate ability to control inflammation and heal. Our first indication is Crohn’s Disease, which affects over 500,000 Americans at an annual cost of $10B. After Crohn's disease, we are going for type 1 Diabetes and Multiple Sclerosis.
    therapeutics
  • Topline Pro
    Topline Pro (W21)Active • 28 employees • New York
    Topline Pro (formerly ProPhone) is a Generative AI platform enabling home service businesses to be easily discovered, trusted and booked, directly. The AI-driven interface rapidly and affordably creates a custom, SEO-optimized website along with a application to help sync content to and from local listings, put social media communications on autopilot and enable the business owner to easily get paid online.
    saas
  • Pangea.app
    Pangea.app (W21)Active • 6 employees • Providence, RI
    The best way to know if someone is a good fit is to work with them on a project before you hire them full-time. At Pangea, we make contract-to-hire easy and painless - with no markup or conversion fees if you hire someone full-time. Browse our curated talent by role, industry experience, and past projects. Our talent have an average of 2-5+ years of experience in design, growth, ops, product, and engineering, and are primarily based in the USA.
    education
    marketplace
    recruiting
  • CoVerified
    CoVerified (W21)Active • 9 employees • Cambridge, MA
    CoVerified builds integrated software that uses COVID-19 test results, vaccine records and symptom data to verify real-time compliance and help organizations re-open safely.
  • Degrees of Freedom
    Degrees of Freedom (W21)Active • 7 employees • Marlboro, VT
    Degrees of Freedom offers a high-quality, low-cost degree, by blending virtual and traditional college models. Our students learn on-campus, and online on-line, and in-VR from diverse Ivy League professors and master teachers-- all at the cost of the Pell Grant
    education
    virtual-reality
    nonprofit
  • SiPhox Health
    SiPhox Health (S20)Active • 25 employees • Burlington, MA
    We are developing a new paradigm for consumer health tech wearables by replacing a 100lb optical instrument with an area of silicon smaller than a postage stamp.
    hard-tech
    biometrics
    nanosensors
    health-tech
    health-&-wellness
  • Nephrogen
    Nephrogen (S20)Active • 1 employees • New York
    We're building curative gene therapies for kidney diseases. Our initial focus is on polycystic kidney disease (PKD), which affects 600,000 Americans and has no effective treatment or cure.
    gene-therapy
    crispr
    biotech
    therapeutics
  • Nabla Bio
    Nabla Bio (S20)Active • 8 employees • Boston
    Our mission is to enable pharmaceutical and biotech companies to bring more antibody therapies to patients. Using AI and massively parallel experimentation, we design antibodies that precisely bind the disease target at the right location, while minimizing manufacturability and toxicity risks. We are a well-funded, revenue-generating, bilingual company of wet- and dry-lab scientists, and are founded by AI and protein design experts from Harvard University.
    ai-powered-drug-discovery
  • Nextera Robotics
    Nextera Robotics (S20)Active • 15 employees • Boston
    Nextera Robotics is an AI-native Robotics and Industrial Automation company founded at MIT.
    artificial-intelligence
    autonomous-delivery
    deep-learning
    robotics
    construction
  • Arist
    Arist (S20)Active • 23 employees • New York
    Arist is the text message learning platform. We help Fortune 500 companies and governments rapidly teach and train employees, entirely via text message.
    education
    elearning
  • Kernal Biologics
    Kernal Biologics (S20)Active • 20 employees • Cambridge, MA
    Kernal Bio creates mRNA 2.0 therapies that instruct specific cells on how to make their own medicine. Kernal Bio encrypts mRNA’s “message” in a language that only cancer cells understand. These tumor-specific mRNA therapeutics allow precise targeting of cancer cells, without harming normal cells or tissues. They have recently been validated in preclinical tumor models, showing high efficacy and safety as well as durable adaptive immunity. With roots at MIT, Harvard and Biopharma, Kernal’s management team has deep expertise in mRNA therapeutics space. CEO Yusuf Erkul, M.D., M.B.A. is a successful drug hunter whose research at Merck enabled an FDA-approved drug for ovarian cancer. President, Burak Yilmaz, M.S., previously founded Sentegen, a thriving synthetic biology company which commercializes synthetic DNA, RNA, and diagnostic kits for genetic and infectious diseases. VP of BD, Matt Strout, M.D. Ph.D., M.B.A, is a business development executive who led more than $4.5B worth of BD deals at Alexion and AstraZeneca. VP of R&D Manfred is a leader in immuno-oncology, who was most recently Scientific Senior Director at Bristol-Myers Squibb (BMS).
    biotech
    genomics
  • OpenBiome
    OpenBiome (W20)Active • 70 employees • Cambridge, MA
    We are a nonprofit stool bank, expanding safe access to fecal transplants and catalyzing research on the human microbiome.
    nonprofit
  • PostEra
    PostEra (W20)Active • 34 employees • Boston
    PostEra is building a modern 21st century biopharma. We're using our advances in machine learning to accelerate Medicinal Chemistry and bring more cures to patients. PostEra advances small molecule programs through partnerships with biopharma while also advancing its own internal pipeline. We've raised $26M from top investors and closed $1Bn in AI partnerships, signing multi-year agreements with Amgen, Pfizer and the NIH. PostEra also launched and led the world's largest open-science drug discovery effort; COVID Moonshot.
    ai-powered-drug-discovery
    machine-learning
    covid-19
  • Multiverse
    Multiverse (W20)Active • 9 employees • Boston
    Multiverse is a web-based game creation system inspired by Dungeons & Dragons and Roblox with a marketplace for assets from A-list creators. We've already partnered with several prominent creators who have millions of followers and millions in revenue, and they're bringing their audiences to Multiverse. We charge 30-60% of those sales based on how much we help the creators make the content. Check out our [gameplay trailer here](https://drive.google.com/file/d/1rPwwhw03HO7uda_YDXBfKfvCZ_fHV795/view?usp=sharing). The best way to get Multiverse is to play it. If you're into games, creativity and representation, hit us up and we'll play with you.
    gaming
  • Metaplane
    Metaplane (W20)Active • 12 employees • Boston
    Metaplane ensures everyone trusts the data that powers your business. Data teams at Bose, Ramp, and Klaviyo use our data observability platform to prevent and detect data issues — before the CEO pings them about weird revenue numbers. We do this with ML-based anomaly detection, end-to-end column-level lineage, and tools to help prevent incidents before they occur. You can monitor your entire data stack within 30 minutes. The company is backed by Khosla Ventures, Y Combinator, and the founders of Okta, HubSpot, and Vercel.
    developer-tools
    saas
    data-engineering
  • Perceptive Technologies, Inc (formerly Cyberdontics)
    Perceptive Technologies, Inc (formerly Cyberdontics) (W20)Active • 3 employees • Boston
    Stealth-mode, rapidly scaling, venture-backed startup at the vanguard of automated robotic surgery revolution -- just closed our Series A round. We are improving access to dental care in underserved populations by combining novel imaging technology with AI and surgical robotics to automate surgery in the $452B dental industry. We are bringing a new imaging modality to dentistry which can see inside teeth and below the gingiva all without the need for x-rays. AI is used to diagnose decay and plan treatment. Automated robotics reduces the time for surgery down to one minute, reducing patient discomfort and saving time and reducing cost for the dentist. YC 2020, Winner of the Forsyth DenTech 2021 CareCaptial award
    artificial-intelligence
    robotics
    health-tech
    medical-devices
  • Gaiascope
    Gaiascope (S19)Active • 9 employees • Boston
    Software that simplifies electric grid forecasting and operations. Clients--hard assets like wind, solar and energy storage--get timely, unbiased information to improve revenues, reduce risk, and maximize the profitability of every megawatt. Gaiascope also manages a quant fund trading electricity; with this fund, the company builds additional credibility with clients and accelerates the continuous improvement of its software.
    climate
    energy
    climatetech
  • Kern Systems
    Kern Systems (S19)Active • 3 employees • Boston
    DNA has emerged as a compelling data storage medium due to its density, longevity, and eternal relevance compared to current memory technologies. However, the high price of synthesizing DNA remains a major bottleneck for adoption of this promising storage solution. We are pioneering new approaches to synthesizing DNA for data storage with enzymes and custom digital codecs. We are building an interdisciplinary team to build the world's most scalable information infrastructure in DNA. We seek technical experts in enzyme engineering, chemistry, hardware engineering, and information theory. We also seek business development to identify emerging markets for early use cases of our technology.
    genomics
    nanotechnology
  • Zeta Surgical
    Zeta Surgical (S19)Active • 10 employees • Boston
    We develop surgical navigation and robotics tools to make minimally invasive surgeries easier, faster and more accessible.
    medical-robotics
    augmented-reality
    ai
  • Memfault
    Memfault (W19)Active • 50 employees • San Francisco
    Memfault is the first IoT reliability platform that empowers teams to build more robust devices with software at scale. We believe that device reliability engineering will transform how developers build and operate IoT and edge devices with more productivity and more collaboration. As IoT applications continue to grow in complexity, it is more important than ever for developers to have Memfault’s performance monitoring, device debugging, and OTA update capabilities built into their fleet of devices for proactive device operations. We built Memfault to enable developers with a more scalable and sustainable process to accelerate go-to-market, de-risk product launches, cut product costs, and deliver overall superior products.
    developer-tools
    saas
    iot
  • 1910 Genetics
    1910 Genetics (W19)Active • 14 employees • Cambridge, MA
    We are a biotechnology company integrating AI, computation and biological automation to accelerate the design of small molecule and protein therapeutics. Our mission is to decrease the timeline and cost of drug development, while improving the success rate of bring innovative medicines to patients in need. We have two drug discovery engines - ELVIS™ and ROSALYND™ - that enable the design of both small molecule and protein therapeutics, an unmatched capability in the AI drug discovery space. Our therapeutic area-agnostic, end-to-end technology powers the full length of early drug discovery - from novel hit discovery to hit to lead, and lead optimization. We are currently applying our technology to drug discovery programs in several areas including, but not limited to, neuroscience, infectious disease, immunology and oncology.
    ai-powered-drug-discovery
  • XGenomes
    XGenomes (W19)Active • 6 employees • Cambridge, MA
    At XGenomes, we are building a technology comprising novel biochemistry, hardware and algorithms for sequencing DNA. Our product will be streamlined: there is zero library preparation; we sequence directly on unadulterated single molecules of DNA; DNA extraction will be integrated with sequencing; there is no bioinformatics bottleneck. The sequence we produce will be of unprecedented accuracy due to several layers of in-built redundancy including the sequencing both strands of the double-helix concurrently. The sequence we produce will be complete, encompassing: structural as well as single nucleotide variants; long-range haplotype phase; the repetitive "dark matter" of the genome. The cost of goods (consumables) of sequencing will be <$10, which will allow us to price our product at a level that will help grow the market while still achieving >90% margin. We will start by offering access as a service to high value customers, which be followed by a razor and blade model of selling instruments and consumables.
    genomics
  • Volta Labs, Inc. (W19)Active • 22 employees • Cambridge, MA
    Volta Labs is a group of antidisciplinary scientists and builders working at the intersection of engineering and biology. We are building a sequencing technology agnostic platform that spans from the raw biological sample to sequenceable molecules. We are doing this by reinventing the full stack — hardware, software, chemistry, and biology — to create simple, flexible, and powerful solutions for sample preparation and beyond.
    hard-tech
    hardware
    biotech
  • Pyxai
    Pyxai (W19)Active • 5 employees • Boston
    Pyxai helps organizations evaluate, identify and source top talent by focusing on the best indicators of long-term job success, soft skills. Our proprietary, AI driven assessment tool helps organizations increase retention by at least 30% all while reducing the time to hire by more than 50%.
    saas
    b2b
  • Community Phone Company
    Community Phone Company (W19)Active • 70 employees • Boston
    Community Phone Company YC W19 built a simple cloud phone system that runs inside of landlines Our solution lets a business or family get all modern voice features (re-route if busy, greeting menu and IVR, programmable caller ID, cloud voicemail, etc) on their existing desk phone and existing cell phones. All employees onboard instantly, no wifi required, no app to download.
    telecommunications
  • Hatch
    Hatch (W19)Active • 73 employees • Richmond, VA
    We are building a SMS business messaging platform for Contact Centers and their teams
    saas
    b2b
  • Ascen
    Ascen (W19)Active • 17 employees • Boston
    Ascen is the modern EOR for staffing firms. Ascen provides employer of record/agent of record services for fast-growing companies, staffing and recruitment firms, and labor marketplaces.
    saas
    b2b
    compliance
    hr-tech
  • Centaur Labs
    Centaur Labs (W19)Active • 25 employees • Boston
    artificial-intelligence
    crowdsourcing
    data-labeling
  • Alpha Vantage
    Alpha Vantage (S18)Active • 8 employees • Boston
    Alpha Vantage provides enterprise-grade financial market data through a set of powerful and developer-friendly data APIs and spreadsheets. Whether you need traditional asset classes (e.g., stocks, ETFs, commodities), economic metrics, foreign exchange rates, cryptocurrencies, fundamental data or even technical indicators, Alpha Vantage is your one-stop shop for global market data delivered through REST APIs.
    artificial-intelligence
    developer-tools
    saas
    analytics
    api
  • Impactive (formerly Outvote)
    Impactive (formerly Outvote) (S18)Active • 15 employees • Boston
    Impactive, backed by YCombinator and Higher Ground Labs, was founded in 2017 as a get-out-the-vote tool for Democrats. The Impactive product has since expanded to become a full-service platform allowing any campaign or cause to engage in distributed organizing. In the 2018 midterms, volunteers contacted over 1 million voters using Impactive. In 2020, we scaled significantly to meet the demand of this unprecedented election cycle. We’ve worked with over 500 clients nationwide, and volunteers have sent over 100 million text messages on behalf of Planned Parenthood, the DCCC, SEIU, Community Change, When We All Vote, Greenpeace, and campaigns up and down the ballot. Our work has been featured in The New York Times, Washington Post, TechCrunch, Fast Company, and many more. In 2021, Impactive will expand its platform further into nonprofit, advocacy, and additional markets. This will be an exciting time to play a critical role in helping shape the direction for what’s coming next. We will continue to prioritize our progressive values while building a feature-rich platform that will broaden our reach across the impact space.
    election-tech
    civic-tech
    govtech
  • Corvus Robotics
    Corvus Robotics (S18)Active • 20 employees • Mountain View
    Our software allows drones to fly indoors and collect analytics, helping warehouses automate inventory collection.
    warehouse-management-tech
    robotics
    drones
    logistics
    supply-chain
  • Apprentice Health
    Apprentice Health (S18)Active • 6 employees • Boston
    We deploy location beacons to track the movements of patients and doctors, measure the inefficiencies in the doctors’ workflows, and then give the hospitals targeted recommendations on how to improve.
    healthcare
  • Reverie Labs
    Reverie Labs (W18)Active • 29 employees • Cambridge, MA
    Reverie Labs is engineering next-generation, brain-penetrant cancer therapies.
    ai-powered-drug-discovery
    machine-learning
    biotech
  • Biobot Analytics
    Biobot Analytics (W18)Active • 17 employees • Cambridge, MA
    Biobot Analytics develops cutting-edge technology to transform sewers into public health observatories. Wastewater contains valuable information about the health of communities. We collect it. We analyze it. We tell you how to leverage it to make your city better. Our first product is to measure opioids and other drug metabolites in sewage to estimate consumption in cities. With this data, those working on harm reduction can assess the scope of the epidemic, allocate resources, and gauge the effectiveness of programming over time.
    health-tech
    analytics
  • Helix Nanotechnologies
    Helix Nanotechnologies (W17)Active • 16 employees • Boston
    Technology finds information and delivers physical products to us almost instantly. mRNA does the same for biology. At HelixNano, we see a world where treatments are cheap, progress is decentralized, and you can modify biology at the push of a button. By focusing on mRNA improvements from first principles, we’re getting there faster than we thought. Experiments that used to take months or years can be done in weeks and cost thousands instead of millions. The rate limiting step for our progress is now scientific curiosity. Rigid hierarchies and top-down decisions will miss the magic. Some of our most powerful technologies started out as side projects of junior team members. At HelixNano, every individual scientist can have a massive impact on the company's direction. And the more diverse our team, the faster we’ll find the really cool ideas. We've started rolling out some of our new tech — moving a COVID-19 vaccine candidate for the immunocompromised towards the clinic, and testing an intervention with massive environmental impact. But we’re scientists at heart, and team focus is solidly on the horizon.
    artificial-intelligence
    biotech
    genomics
    nanotechnology
  • Tolemi
    Tolemi (W17)Active • 16 employees • Boston
    A smart city technology product company that helps state and local governments take a data-driven approach to rebuild cities and towns.
    civic-tech
    govtech
  • Kaymbu (IK12)Active • 11 employees • Boston
    Kaymbu is the leading visual messaging and authentic assessment platform for early education. From photo sharing to student portfolios, school newsletters and dynamic photo books, Kaymbu connects early childhood educators with young, digital-native parents. Kaymbu captures the essence of student development and strengthens relationships between home and school.
  • Raptor Maps (S16)Active • 60 employees • Somerville, MA
    Solar power is the #1 source of new energy in the world. Raptor Maps is a fast-growing, MIT-born startup that builds software to manage the solar lifecycle. We are deployed across 45 countries and 200+ million solar panels. Our software enables the solar industry to scale. We're headquartered at Greentown Labs, the largest cleantech incubator in the US and also support fully remote employees.
    solar-power
    climate
    renewable-energy
  • TetraScience
    TetraScience (S15)Active • 100 employees • Boston
    TetraScience provides the world’s first and only R&D Data Cloud, with a mission to transform life sciences R&D, accelerate discovery, and improve human life. Scientists at global pharma and biotech organizations rely on our innovative Tetra Data Platform for easy access to centralized, harmonized, and actionable scientific data to accelerate their digital lab transformation. With best-in-class SaaS performance, a team of industry innovators, and excellent product/market fit, Tetra is positioned to become an iconic life sciences software company.
    saas
    data-engineering
  • NewsBlur
    NewsBlur (S12)Active • 1 employees • Cambridge, MA
    NewsBlur is a personal news reader that brings people together to talk about the world. A new sound of an old instrument.
    consumer
  • Aptible
    Aptible (S14)Active • 25 employees • San Francisco
    At Aptible, we envision a world where developers achieve more with less infrastructure. We’re building the platform that empowers developers at companies of all stages of development to move beyond the traditional method of managing infrastructure—DIY with expert infrastructure and platform engineers on AWS, GCP, or Azure. We’ve done this through our secure, compliant, reliable, and scalable Platform as a Service that’s been used by thousand of developers, hundreds of companies, and dozens of publicly traded and unicorn companies since 2013.
    developer-tools
    devsecops
    devops
    web-development
    cloud-computing
  • Stackshine
    Stackshine (W22)Acquired • 7 employees • Portland, OR
    Stackshine is creating mission control for enterprise IT teams. We discover all the software being used across their organization and then automate workflows related to onboarding/offboarding, cost savings, and security.
    robotic-process-automation
    productivity
    analytics
    enterprise
    data-engineering
  • inBalance
    inBalance (W21)Acquired • 10 employees • Cambridge, MA
    We use machine learning to accurately forecast electricity prices. Our live customers, including Enel, use our software to improve revenue by millions of dollars per year.
    energy-storage
    saas
    climate
  • Swipehouse
    Swipehouse (W18)Acquired • 5 employees • Cambridge, MA
    The biggest social network in the world for TikTok celebs. One of the first 5 companies in the US to get the TikTok API. Launched over 400 companies on TikTok in over a year,
    entertainment
    community
    e-commerce
  • Medumo
    Medumo (W18)Acquired • 12 employees • Boston
    We’re a group of Harvard and Yale-trained physicians, engineers, designers, and social entrepreneurs who came together to transform care delivery. Medumo’s CareTours™ enable healthcare organizations to effectively provide turn-by-turn guidance to patients without disrupting workflow by utilizing automated, precisely-timed messages sent via text and email. - Dramatically improve procedural completion rate - Increase referral conversion - Reduce staff burden - Recover revenue loss Want to get started in automating patient navigation for your Hospital, ASC, or Practice? We serve all specialties. Reach out to our leadership team for a brief chat or full presentation. Bob Smith - Director Strategic Partnerships Bob@medumo.com Cell # is 502-744-2911 EST
    healthcare
    healthcare-it
  • Hunter2 (W18)Acquired0 • Boston
    Hunter2 teaches modern appsec to engineering teams through interactive labs. Developers get hands-on practice exploiting and patching real web apps written in their tech stack.
    developer-tools
    education
    cybersecurity
  • Pretty Instant
    Pretty Instant (W15)Acquired • 3 employees • Boston
    Pretty Instantly streamlines the photography needs of over 2000 forward-thinking brands and non-profits. By handling all of the back-end logistics, staffing, editing, and delivery of photos for our clients, as well as building Interactive photography technology, Pretty Instant is the go-to solution for growing companies and reputable brands nationwide.
    b2b
  • Moltin (W15)Acquired • 32 employees • Boston
    At Moltin, we believe that brand experiences should never be obscured by technology and that commerce development should be simple, lightweight and fun. Moltin is an API-first digital commerce solution that enables retailers to build distinctive shopping experiences and embed them into any consumer touchpoint. It combines an extremely flexible set of APIs, developer toolkits, pre-built applications and cloud infrastructure to make commerce development simple, lightweight and fast. Moltin APIs are the simplest, most powerful in the industry. Retailers can test new channels quickly, scale into new markets, and keep pace with ever-evolving consumer trends. With Moltin, commerce flows seamlessly across any channel, device and experience. Moltin has a rapidly growing community of more than 17,000 developers around the world, pushing the boundaries of traditional commerce.
    payments
    e-commerce
    api
  • Kiko
    Kiko (S05)Acquired0 • Cambridge, MA
    Kiko is a web calendar for anyone who wants to keep and share a calendar online. Kiko excels at three main things: * Universal access: Kiko integrates with your mobile phone and AIM and lets you access your calendar from any computer. * Share your calendar: Invite anyone to events (not just other Kiko users!) Let others view your calendar with just a click. * As easy as paper - or maybe easier: Write "Pay gas bill every month" onto your calendar and watch Kiko do the Right Thing!
    calendar
  • Embedly (W10)Acquired • 2 employees • Boston
    Embedly provides a platform and suite of tools to make embedding and previewing links simple. Embedly helps publishers and consumers manage embed codes from more than 100 Websites and APIs, including YouTube, Flickr, Ustream, Picassa, Hulu, Twitpic, Quantcast, and CrunchBase. It automatically convert links from these sources into embedded media on the fly.
  • Cloudant (S08)Acquired • 51 employees • Boston
    Cloudant's distributed database-as-a-service (DBaaS) allows developers of fast-growing web and mobile apps to focus on building and improving their products, instead of worrying about scaling and managing their databases on their own. We manage and distribute your data globally so you can grow more users, build more app features, and sleep more knowing we're keeping the servers up and humming. Cloudant was founded in Cambridge, Massachusetts in 2008 by three MIT physicists who at the time were moving multi-petabyte data sets around from the Large Hadron Collider. Frustrated by the available tools for managing and analyzing Big Data in their research, the founders built a distributed, fault-tolerant, globally scalable data layer on top of Apache CouchDB. The service has grown since then. The team now manages and serves mobile and web app data on behalf of thousands of developers and hundreds of customers to their users around the world. In 2014, the company was acquired by a global enterprise software & hardware vendor.